GWAS results in the Diabetes Prevention Program EXTENSION OF TYPE 2 DIABETES GENOME-WIDE ASSOCIATION SCAN RESULTS IN THE DIABETES PREVENTION PROGRAM
نویسندگان
چکیده
1 Center for Human Genetic Research and 2 Diabetes Center, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; 3 Department of Medicine, Harvard Medical School, Boston, Massachusetts; 4 Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts; 5 The Biostatistics Center, George Washington University, Rockville, Maryland; 6 Department of Medicine, Division of Endocrinology, Diabetes & Nutrition University of Maryland School of Medicine; 7 Genetic Epidemiology & Clinical Research Group, Department of Public Health and Clinical Medicine, Division of Medicine, Umeå University Hospital, Umeå, Sweden; 8 Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona; 9 Department of Genetics, Harvard Medical School, Boston, Massachusetts (*) A list of Diabetes Prevention Program Research Group investigators is provided in the Online Appendix
منابع مشابه
Genetics of Type 2 Diabetes- A Review Article
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OBJECTIVE Genome-wide association scans (GWASs) have identified novel diabetes-associated genes. We evaluated how these variants impact diabetes incidence, quantitative glycemic traits, and response to preventive interventions in 3,548 subjects at high risk of type 2 diabetes enrolled in the Diabetes Prevention Program (DPP), which examined the effects of lifestyle intervention, metformin, and ...
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